Novel mutations in familial dilated cardiomyopathy identified by whole exome sequencing [abstract 696].
Digoxin is a cardiac glycoside with direct inotropic effects in addition to indirect effects on the cardiovascular system. It is intended for general informational purposes only and does not address individual circumstances. Once diagnosed, the primary goal is to improve cardiac function and reduce symptoms. Outcomes in catheter ablation of ventricular tachycardia in dilated nonischemic cardiomyopathy compared with ischemic cardiomyopathy: results from the Prospective Heart Centre of Leipzig VT (HELP-VT) Study. Not all antiarrhythmics are considered safe in patients with structural heart disease. Advanced heart failure treated with continuous-flow left ventricular assist device.
Mancini DM, Eisen H, Kussmaul W, Mull R, Edmunds LH Jr, Wilson JR. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Ommen SR, Nishimura RA, Edwards WD. It is indicated for temporary treatment of edema associated with heart failure when greater diuretic potential is needed. Diseases & Conditions To what extent do congestive heart failure patients in sinus rhythm benefit from digoxin therapy?
There is no information on use of this drug for heart rates less than 50 beats per minute.Preload reduction with venodilators is thought to be helpful in acute decompensated heart failure by reducing congestions and minimizing cardiac oxygen demand.
Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). It helps prevent potassium loss in distal tubules. CIBIS-II Investigators and Committees. The Xamoterol in Severe Heart Failure Study Group. Clinical utility and prognostic value of left atrial volume assessment by cardiovascular magnetic resonance in non-ischaemic dilated cardiomyopathy. Nesiritide is a human BNP.Carvedilol blocks beta1-, alpha-, and beta2-adrenergic receptor sites, decreasing adrenergic-mediated myocyte damage.Metoprolol is a selective beta1-adrenergic receptor blocker that decreases automaticity of contractions. Cooper LT Jr, Berry GJ, Shabetai R. Idiopathic giant-cell myocarditis--natural history and treatment. Wegener's granulomatosis and the heart. Freudenberger RS, Hellkamp AS, Halperin JL, et al, for the SCD-HeFT Investigators. The role of right ventricular endomyocardial biopsy for idiopathic giant cell myocarditis. Costanzo MR, Augustine S, Bourge R, et al. General guidelines for initiating beta-blocker therapy include treating all patients with left ventricular dysfunction except those who are acutely decompensated.
Effects of losartan versus captopril on mortality in patients with symptomatic heart failure: rationale, design, and baseline characteristics of patients in the Losartan Heart Failure Survival Study--ELITE II.
Diagnosis and management of the cardiac amyloidoses. Renal effects include diuresis and natriuresis with at least preservation, if not an increase, in renal blood flow and glomerular filtration rate. Francone M. Role of cardiac magnetic resonance in the evaluation of dilated cardiomyopathy: diagnostic contribution and prognostic significance. Improvement of CHF symptoms occurs as the trade-off for this increase in mortality. Peak exercise oxygen consumption in chronic heart failure: toward efficient use in the individual patient. Van Bommel RJ, Mollema SA, et al. Guinn MM, Bedford JA, Wilson MC.
Uemura A, Morimoto S, Hiramitsu S, Kato Y, Ito T, Hishida H. Histologic diagnostic rate of cardiac sarcoidosis: evaluation of endomyocardial biopsies.
Venous and arterial dilation results in decreased preload and afterload and reductions in pulmonary capillary wedge pressure.
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