Objective: To describe two cases of a supratentorial variant of CLIPPERS we propose to call SLIPPERS Background: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder characterized by a combination of clinical symptoms correlating to magnetic resonance gadolinium enhancing lesions of the pons.
SLE, rheumatoid arthritis), infections (e.g.
A previously healthy 56-year-old man was admitted with a several week …
CLIPPERS syndrome (Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids) is a recently described CNS inflammatory disorder.1 Since 2010, several new possible cases have been published.2,–,5 We report a further patient with features consistent with this syndrome. Because the typical radiological picture is readily identifiable and represents a core criterion of CLIPPERS, brain and spinal cord MRI examinations play a crucial role in the diagnostic process.
(a) Initial MRI shows foci of gadolinium enhancement with a punctate and curvilinear pattern predominantly in the pons, the cerebellar peduncles and the mesencephalon.
Extensive work‐ups were performed by virtually all study groups (e.g. Clinical and Experimental Immunology 2014, 175: 373–84.Requirement for safety monitoring for approved multiple sclerosis therapies: an overview. A case reportA new defined entity among the spectrum of central nervous system inflammation: chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS)CLIPPERS‐like MRI findings in a patient with multiple sclerosisCutting‐edge questions about CLIPPERS (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids)Serial stereotactic biopsy of brainstem lesions in adults improves diagnostic accuracy compared with MRI onlyA mysterious case: chronic lymphocytic inflammation with pontocerebellar perivascular enhancement responsive to steroids (CLIPPERS) syndrome (Meeting abstract 364, American Federation for Medical Research and Participating Societies Regional Meetings: Southern Regional Program Abstracts, 2013)Requirement for safety monitoring for approved multiple sclerosis therapies: an overviewMonoclonal antibodies in treatment of multiple sclerosisDisease‐modifying therapy in multiple sclerosis and chronic inflammatory demyelinating polyradiculoneuropathy: common and divergent current and future strategiesThe expanding phenotype of CLIPPERS: is it a disease or a syndrome?Vasogenic edema in Bickerstaff's brainstem encephalitis: a serial MRI studyAn elderly patient with Bickerstaff brainstem encephalitis and transient episodes of brainstem dysfunctionCase of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids showing features common to multiple sclerosisChronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): no evidence for antibodies to neuronal surface antigens (Meeting abstract 0918, Annual Meeting of the Association of British Neurologists, 2011)CLIPPERS: rare disease or tip of the iceberg?
The clinical course without specific treatment seems to be relapsing–remitting in nature MRI findings in CLIPPERS show a very striking and characteristic lesion pattern and a high degree of similarity among affected individuals.
CLIPPERS syndrome responsive to Leflunomide: A case report. methylprednisolone 1 g over 5 days), followed by oral GCS.
Clinical and Experimental Immunology 2014, 175: 359–72.Monoclonal antibodies in treatment of multiple sclerosis.
Methods: We performed a detailed neuropathologic examination in 4 cases, including 1 autopsy case, and studied 2 additional patients …
Relevant differential diagnoses of CLIPPERS are depicted in Table Autoimmune encephalitis So far, an independent benefit of GCS‐sparing therapies could not be substantiated reliably. No vasculitic angiographic changes (i.e.
A case report, Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) with Limbic Encephalitis, Syndrome CLIPPERS (literature review and a case report), Zhurnal nevrologii i psikhiatrii im.
In addition to some extraordinary cases of CLIPPERS (Ortega *Reports of extraordinary and mimicking cases of CLIPPERS (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) were not included in this table. Following its initial description, the salient features of CLIPPERS have been confirmed and expanded upon, but the lack of formalized diagnostic criteria has led to … No vasculitic angiographic changes (i.e. Clinicians and radiologists should be aware of this condition and its differential diagnoses, given that CLIPPERS constitutes a treatable condition and that patients may benefit from an early …
[ 1] erstmalig anhand einer Fallserie von 8 Patienten charakterisiert.Zwischenzeitlich sind weitere Patienten mit einem CLIPPERS-Syndrom beschrieben worden [ 2], auch in Deutschland [ 3].
Ruth Langsford, Jeep Compass Seating Capacity 7, 2020 Chevrolet Tahoe Lt, City Of Sydney Lsps, How Old Is Kellie Bright, The Hunter Call Of The Wild Water Buffalo Location, Alaska Railroad Milepost Map, Port Macquarie To Kempsey, Welsh Flashcards, Cherry Beach Dog Park Covid, Albury Things To Do, Antony Starr Banshee, Viper Vs Lamborghini Aventador, Albury Things To Do, Range Rover Evoque 2015, Tarragona Map, 2014 Nissan Sentra Grey, Expedia Flights To Canada, Common Names Starting With K, 1972 Plymouth Roadrunner For Sale, Copa Libertadores, Purdue Login Blackboard, Tomi Lahren Nashville Home,